Uberon definition : The fluid-filled cavity that lies between the visceral and parietal pleurae.;
Uberon Function note : The contraction of the diaphragm creates a negative pressure within the pleural cavity
which forces the lungs to expand resulting in passive exhalation and active inhalation.
This breathing process can be made forceful through the contraction of the external
intercostal muscles which forces the rib cage to expand and add to the negative pressure
in the pleural cavity causing the lungs to fill with air. The fluid in the cavity
provides lubrication and cushioning;
Uberon Homology note : In hagfishes a transverse septum extends upward from the ventral body wall posterior
to the heart, partly separating an anterior pericardial cavity from a larger peritoneal
cavity. (...) These basic relationships have not been modified by urodeles. The small
pericardial cavity remains far forward where it is separated by a transverse septum
from the principal coelom, which may now be called a pleuroperitoneal cavity because
slender lungs are present. (...) The heart [of other tetrapods] is separated from
the lungs (and liver if present) by more or less horizontal partitions that have their
origin in the embryo as folds on the serous membrane of the right and left lateral
body walls. These grow out to join in the midline of the body. They are called lateral
mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse
septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning
of their coelom, embryonic mammals resemble first early fishes (incomplete partition,
posterior to heart, consisting of the transverse septum) and then reptiles (pericardium
derived from transverse septum and pleuropericardial membranes). Mammals then separate
paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion
of this organ comes from the transverse septum. The dorsal portion is derived from
the dorsal mesentery and from still another pair of outgrowths from the lateral body
wall, the pleuroperitoneal membranes.[well established][VHOG];