Uberon definition : Either of a pair of complex endocrine organs near the anterior medial border of the
kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid,
and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO].;
Uberon Function note : suprarenal cortex manufactures corticosteroids; suprarenal medulla manufactures epinephrine
and norepinephrine; suprarenal medulla receives preganglionic sympathetic innervation
from the greater thoracic splanchnic n.;
Uberon Homology note : All craniates have groups of cells homologous to the mammalian adrenocortical and
chromaffin tissues, but they are scattered in and near the kidneys in fishes. (...)
The cortical and chromaffin tissues come together to form adrenal glands in tetrapods.[well
established][VHOG];
Uberon Taxon note : The origin of the adrenal gland is still controversial. It is thought to share the
same origin as the kidney and gonads, derived from coelomic epithelium of the urogenital
ridge and/or the underlying mesenchyme (Keegan and Hammer, 2002; Morohashi, 1997).
We follow Kardong and state homology at the level of the cortex and medulla rather
than gland as a whole;
Either of a pair of complex endocrine organs near the anterior medial border of the
kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid,
and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO].