Preferred Label : tympanic membrane;
Uberon definition : A thin membrane that separates the external ear from the middle ear, consisting of
two epithelia (one part of the the external accoustic meatus epithelium, the other
part of the tympanic cavity epithelium) with a fibrous layer between them. Its function
is to transmit sound from the air to the ossicles inside the middle ear. The malleus
bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation
of the eardrum can lead to conductive hearing loss. [WP,unvetted].;
Uberon synonym : lateral wall of tympanic cavity; Rivinus' membrane; eardrum; ear drum; membranous wall of tympanic cavity; myrinx;
Uberon related term : tympanum;
Uberon Development note : The tympanic membrane (TM) has three layers, two epithelia provided by the external
acoustic meatus (EAM) and the MEC, derived respectively from the first pharyngeal
cleft and pouch, and a mesenchymally derived fibrous stratum;
Uberon Homology note : In particular, a tympanic membrane was not present in the earliest tetrapods (...).
An ear utilizing a tympanic membrane evolved independently at least three times in
tetrapods: (1) in the lineage that leads to anurans (frogs), (2) in the line of evolution
to turtles and diapsids, and (3) in the late synapsid lineage that gave rise to mammals.[well
established][VHOG];
Origin ID : 0002364;
UMLS CUI : C0041445;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Uberon cross reference
- adjacent to
- contributes to morphology of
- develops from
- has part
- part of
- surrounded by
- surrounds
A thin membrane that separates the external ear from the middle ear, consisting of
two epithelia (one part of the the external accoustic meatus epithelium, the other
part of the tympanic cavity epithelium) with a fibrous layer between them. Its function
is to transmit sound from the air to the ossicles inside the middle ear. The malleus
bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation
of the eardrum can lead to conductive hearing loss. [WP,unvetted].
