Uberon definition : The midbrain is the middle division of the three primary divisions of the developing
chordate brain or the corresponding part of the adult brain (in vertebrates, includes
a ventral part containing the cerebral peduncles and a dorsal tectum containing the
corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third
and fourth ventricles)[GO].;
Uberon broad term : MB;
Uberon Homology note : Fine structural, computerized three-dimensional (3D) mapping of cell connectivity
in the amphioxus nervous system and comparative molecular genetic studies of amphioxus
and tunicates have provided recent insights into the phylogenetic origin of the vertebrate
nervous system. The results suggest that several of the genetic mechanisms for establishing
and patterning the vertebrate nervous system already operated in the ancestral chordate
and that the nerve cord of the proximate invertebrate ancestor of the vertebrates
included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG];
The midbrain is the middle division of the three primary divisions of the developing
chordate brain or the corresponding part of the adult brain (in vertebrates, includes
a ventral part containing the cerebral peduncles and a dorsal tectum containing the
corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third
and fourth ventricles)[GO].