Uberon definition : The thin layer of gray matter on the surface of the cerebral hemisphere that develops
from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex),
the hippocampal formation and the olfactory cortex.;
Uberon synonym : cortex of cerebral hemisphere;
Uberon related term : cortical plate (CTXpl); brain cortex; cortical plate (areas); pallium of the brain;
Uberon Homology note : Migration of neurons from the basal or striatal portions of the anterior part of the
neural tube occurs to varying degrees in different vertebrate classes, but a true
cerebral cortex is generally acknowledged to have made its first appearance in reptiles.
The definition can be unambiguous, since 'cortex' simply implies the existence of
a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing
dendrites and axons, which is separated from the underlying basal 'matrix' by white
matter. Although reptilian cerebral cortex does indeed fulfill these conditions in
certain locations, the separation from striatal structures is often indistinct, so
that it may even be argued that some primitive dipnoans possess a pallium or cortex.
Nevertheless, an extensive laminated layer separated by underlying white matter is
well represented only in reptiles and mammals.[well established][VHOG];
Uberon Taxon note : hagfishes have independently evolved a highly laminated cerebral cortex, comparable
in many ways to the cerebral cortex of mammals [http://icb.oxfordjournals.org/content/42/4/743];
The thin layer of gray matter on the surface of the cerebral hemisphere that develops
from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex),
the hippocampal formation and the olfactory cortex.