Preferred Label : multiple system atrophy;
RADLEX synonyms : Shy-Drager disease; multisystem atrophy;
Definition : A syndrome complex composed of three conditions which represent clinical variants
of the same disease process: striatonigral degeneration; shy-drager syndrome; and
the sporadic form of olivopontocerebellar atrophies. Clinical features include autonomic,
cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy
of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic
neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology,
6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999
Mar;83(2):381-92) [MeSH];
UMLS CUI (RADLEX) : C0393571;
Origin ID : RID5158;
UMLS CUI : C0393571;
Associated condition of
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
A syndrome complex composed of three conditions which represent clinical variants
of the same disease process: striatonigral degeneration; shy-drager syndrome; and
the sporadic form of olivopontocerebellar atrophies. Clinical features include autonomic,
cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy
of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic
neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology,
6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999
Mar;83(2):381-92) [MeSH]
