Preferred Label : frontotemporal dementia;
RADLEX synonyms : Pick disease; FTD;
Definition : A rare form of dementia that is sometimes familial. Clinical features include aphasia;
apraxia; confusion; anomia; memory loss; and personality deterioration. This pattern
is consistent with the pathologic findings of circumscribed atrophy of the poles of
the frontal lobe and temporal lobe. Neuronal loss is maximal in the hippocampus, entorhinal
cortex, and amygdala. Some ballooned cortical neurons contain argentophylic (Pick)
bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology,
6th ed, pp1057-9) [MeSH];
Origin ID : RID5140;
UMLS CUI : C0338451;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
A rare form of dementia that is sometimes familial. Clinical features include aphasia;
apraxia; confusion; anomia; memory loss; and personality deterioration. This pattern
is consistent with the pathologic findings of circumscribed atrophy of the poles of
the frontal lobe and temporal lobe. Neuronal loss is maximal in the hippocampus, entorhinal
cortex, and amygdala. Some ballooned cortical neurons contain argentophylic (Pick)
bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology,
6th ed, pp1057-9) [MeSH]