Preferred Label : central pontine myelinolysis;
RADLEX synonyms : CPM;
Definition : A demyelinating condition affecting the pons and characterized clinically by an acute
progressive quadriplegia; dysarthria; dysphagia; and alterations of consciousness.
Pathologic features include prominent demyelination in the central pons with sparing
of axons and neurons. This condition is usually associated with systemic disorders
such as hyponatremia; chronic alcoholism; liver failure; severe burns; malignant neoplasms;
hemorrhagic pancreatitis; hemodialysis; and sepsis. The rapid medical correction of
hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles
of Neurology, 6th ed, pp1125-6) [MeSH];
UMLS CUI (RADLEX) : C0206083;
Origin ID : RID5050;
UMLS CUI : C0206083;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
A demyelinating condition affecting the pons and characterized clinically by an acute
progressive quadriplegia; dysarthria; dysphagia; and alterations of consciousness.
Pathologic features include prominent demyelination in the central pons with sparing
of axons and neurons. This condition is usually associated with systemic disorders
such as hyponatremia; chronic alcoholism; liver failure; severe burns; malignant neoplasms;
hemorrhagic pancreatitis; hemodialysis; and sepsis. The rapid medical correction of
hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles
of Neurology, 6th ed, pp1125-6) [MeSH]
