Preferred Label : myelinolysis, central pontine;
MeSH definition : A demyelinating condition affecting the PONS and characterized clinically by an acute
progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness.
Pathologic features include prominent demyelination in the central PONS with sparing
of axons and neurons. This condition is usually associated with systemic disorders
such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS;
hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of
hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles
of Neurology, 6th ed, pp1125-6);
MeSH synonym : central pontine myelinolysis; myelinoclasis, central pontine; pontine myelinolysis, central; central pontine myelinoclasis;
Related MeSH term : extrapontine myelinolysis; Extrapontine Myelinolyses; Myelinolyses, Extrapontine; Myelinolysis, Extrapontine; Extrapontine Myelinoclasis; Extrapontine Myelinoclases; Myelinoclases, Extrapontine; Myelinoclasis, Extrapontine;
Wikipedia link : https://en.wikipedia.org/wiki/Myelinolysis, central pontine;
Origin ID : D017590;
UMLS CUI : C0206083;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- DO Cross reference
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
A demyelinating condition affecting the PONS and characterized clinically by an acute
progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness.
Pathologic features include prominent demyelination in the central PONS with sparing
of axons and neurons. This condition is usually associated with systemic disorders
such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS;
hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of
hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles
of Neurology, 6th ed, pp1125-6)
