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Preferred Label : thecoma;

RADLEX synonyms : fibrothecoma;

Definition : A gonadal stromal neoplasm composed only of theca cells, occurring mostly in the postmenopausal ovary. It is filled with lipid-containing spindle cells and produces estrogens that can lead to endometrial hyperplasia; uterine hemorrhage; or other malignancies in postmenopausal women and sexual precocity in girls. When tumors containing theca cells also contain fibroblasts, they are identified as thecoma-fibroma tumors with less active hormone production. [MeSH];

UMLS CUI (RADLEX) : C0039747;

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A gonadal stromal neoplasm composed only of theca cells, occurring mostly in the postmenopausal ovary. It is filled with lipid-containing spindle cells and produces estrogens that can lead to endometrial hyperplasia; uterine hemorrhage; or other malignancies in postmenopausal women and sexual precocity in girls. When tumors containing theca cells also contain fibroblasts, they are identified as thecoma-fibroma tumors with less active hormone production. [MeSH]

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18/05/2024


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