MeSH definition : A gonadal stromal neoplasm composed only of THECA CELLS, occurring mostly in the postmenopausal
OVARY. It is filled with lipid-containing spindle cells and produces ESTROGENS that
can lead to ENDOMETRIAL HYPERPLASIA; UTERINE HEMORRHAGE; or other malignancies in
postmenopausal women and sexual precocity in girls. When tumors containing theca cells
also contain FIBROBLASTS, they are identified as thecoma-fibroma tumors with less
active hormone production.;
A gonadal stromal neoplasm composed only of THECA CELLS, occurring mostly in the postmenopausal
OVARY. It is filled with lipid-containing spindle cells and produces ESTROGENS that
can lead to ENDOMETRIAL HYPERPLASIA; UTERINE HEMORRHAGE; or other malignancies in
postmenopausal women and sexual precocity in girls. When tumors containing theca cells
also contain FIBROBLASTS, they are identified as thecoma-fibroma tumors with less
active hormone production.