Preferred Label : astrocytoma WHO grade IV;
RADLEX synonyms : glioblastoma multiforme;
Definition : A malignant form of astrocytoma histologically characterized by pleomorphism of cells,
nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the
central nervous system, with a predilection for the cerebral hemispheres, basal ganglia,
and commissural pathways. Clinical presentation most frequently occurs in the fifth
or sixth decade of life with focal neurologic signs or seizures. [MeSH];
RADLEX acronyms : GBM;
UMLS CUI (RADLEX) : C0017636;
Origin ID : RID4044;
UMLS CUI : C0017636;
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A malignant form of astrocytoma histologically characterized by pleomorphism of cells,
nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the
central nervous system, with a predilection for the cerebral hemispheres, basal ganglia,
and commissural pathways. Clinical presentation most frequently occurs in the fifth
or sixth decade of life with focal neurologic signs or seizures. [MeSH]