Definition : A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation
of all hematopoietic bone marrow elements and an absolute increase in red cell mass
and total blood volume, associated frequently with splenomegaly, leukocytosis, and
thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and
spleen). In time myelofibrosis occurs. [MeSH];
A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation
of all hematopoietic bone marrow elements and an absolute increase in red cell mass
and total blood volume, associated frequently with splenomegaly, leukocytosis, and
thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and
spleen). In time myelofibrosis occurs. [MeSH]