Preferred Label : Guillain-Barre syndrome;
RADLEX synonyms : acute inflammatory demyelinating polyradiculoneuropathy;
Definition : An acute inflammatory autoimmune neuritis caused by T cell-mediated cellular immune
response directed towards peripheral myelin. Demyelination occurs in peripheral nerves
and nerve roots. The process is often preceded by a viral or bacterial infection,
surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations
include progressive weakness, loss of sensation, and loss of deep tendon reflexes.
Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et
al., Principles of Neurology, 6th ed, pp1312-1314) [MeSH];
UMLS CUI (RADLEX) : C0018378;
Origin ID : RID3465;
UMLS CUI : C0018378;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
An acute inflammatory autoimmune neuritis caused by T cell-mediated cellular immune
response directed towards peripheral myelin. Demyelination occurs in peripheral nerves
and nerve roots. The process is often preceded by a viral or bacterial infection,
surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations
include progressive weakness, loss of sensation, and loss of deep tendon reflexes.
Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et
al., Principles of Neurology, 6th ed, pp1312-1314) [MeSH]
