Preferred Label : keratin;
Definition : A class of fibrous proteins or scleroproteins important both as structural proteins
and as keys to the study of protein conformation. The family represents the principal
constituent of epidermis, hair, nails, horny tissues, and the organic matrix of tooth
enamel. Two major conformational groups have been characterized, alpha-keratin, whose
peptide backbone forms an alpha-helix, and beta-keratin, whose backbone forms a zigzag
or pleated sheet structure. [MeSH];
UMLS CUI (RADLEX) : C0022564;
Origin ID : RID1550;
UMLS CUI : C0010803;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
A class of fibrous proteins or scleroproteins important both as structural proteins
and as keys to the study of protein conformation. The family represents the principal
constituent of epidermis, hair, nails, horny tissues, and the organic matrix of tooth
enamel. Two major conformational groups have been characterized, alpha-keratin, whose
peptide backbone forms an alpha-helix, and beta-keratin, whose backbone forms a zigzag
or pleated sheet structure. [MeSH]
