Preferred Label : keratins;
MeSH definition : A class of fibrous proteins or scleroproteins that represents the principal constituent
of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL.
Two major conformational groups have been characterized, alpha-keratin, whose peptide
backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN
and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated
sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In
addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.;
MeSH synonym : keratin; cytokeratin;
MeSH hyponym : keratin, glycosylated; Keratin-Associated proteins; alpha-Keratin; Glycosylated Keratin; Keratin Associated Proteins; alpha Keratin; Keratin Associated Protein; Associated Protein, Keratin; Protein, Keratin Associated;
MeSH Related Number : 9008-18-8 (other number);
Registry Number MeSH : 68238-35-7;
Wikipedia link : https://en.wikipedia.org/wiki/Keratin;
Codes EINECS : 269-409-1;
Is substance : O;
Origin ID : D007633;
UMLS CUI : C0010803;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
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- See also
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
A class of fibrous proteins or scleroproteins that represents the principal constituent
of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL.
Two major conformational groups have been characterized, alpha-keratin, whose peptide
backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN
and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated
sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In
addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
