SENP1/MESDC2 Fusion Protein

Preferred Label : SENP1/MESDC2 Fusion Protein;

NCIt synonyms : SENP1-MESDC2 Fusion Protein; SEME; Sentrin-Specific Protease 1/LDLR Chaperone MESD Fusion Protein; SENP1::MESD Fusion Protein; SENP1::MESDC2 Fusion Protein;

NCIt definition : A fusion protein encoded by the SENP1/MESDC2 fusion gene. This protein is comprised of the extreme N-terminus of the sentrin-specific protease 1 protein fused to all but the first 71 or 106 amino acids of the LDLR chaperone MESD protein.;

NCIt note : The SENP1/MESDC2 fusion protein does not have the activity of the LDLR chaperone MESD because the fusion protein is not localized to the endoplasmic reticulum. (Hum. Mol. Genet. 2005; 14: 1955-1963.);

PubMed : 15917269;

Details

Origin ID

C99842;

UMLS CUI

C3274997;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- SENP1/MESDC2 Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- MESD Gene [NCIt concept]
- SENP1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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