" /> EML4/ALK Fusion Protein Variant 5b - CISMeF





Preferred Label : EML4/ALK Fusion Protein Variant 5b;

NCIt synonyms : EML4-ALK Fusion Protein Variant 5b; Fusion Protein EML4-ALK Variant 5 Splicing Isoform b; Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 5b; EML4::ALK Fusion Protein Variant 5b;

NCIt definition : A fusion protein (671 aa, 74 kDa) that is encoded by the EML4/ALK variant 5b fusion gene. This protein is comprised of the N-terminal half of the echinoderm microtubule-associated protein-like 4 fused to the entire cytoplasmic domain of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.;

NCIt note : The EML4/ALK fusion protein variant 5b is a constitutively dimerized and activated tyrosine kinase.;

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15/05/2024


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