" /> EML4/ALK Fusion Protein Variant 5a - CISMeF





Preferred Label : EML4/ALK Fusion Protein Variant 5a;

NCIt synonyms : EML4-ALK Fusion Protein Variant 5a; Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 5a; Fusion Protein EML4-ALK Variant 5 Splicing Isoform a; EML4::ALK Fusion Protein Variant 5a;

NCIt definition : A fusion protein (630 aa, 70 kDa) that is encoded by the EML4/ALK variant 5a fusion gene. This protein is comprised of the extreme N-terminus of the echinoderm microtubule-associated protein-like 4 fused to the entire cytoplasmic domain of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.;

NCIt note : The EML4/ALK fusion protein variant 5a is a constitutively dimerized and activated tyrosine kinase.;

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15/05/2024


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