" /> EML4/ALK Fusion Protein Variant 3b - CISMeF





Preferred Label : EML4/ALK Fusion Protein Variant 3b;

NCIt synonyms : EML4-ALK Fusion Protein Variant 3b; Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 3b; Fusion Protein EML4-ALK Variant 3 Splicing Isoform b; EML4::ALK Fusion Protein Variant 3b;

NCIt definition : A fusion protein (796 aa, 88 kDa) that is encoded by the EML4/ALK variant 3b fusion gene. This protein contains the amino acids encoded by exons 1-6b of the echinoderm microtubule-associated protein-like 4 and the entire cytoplasmic region of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.;

NCIt note : The EML4/ALK fusion protein variant 3b is a constitutively dimerized and activated tyrosine kinase.;

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15/05/2024


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