GOPC/ROS1 Fusion Gene

Preferred Label : GOPC/ROS1 Fusion Gene;

NCIt synonyms : FIG1/ROS1 Fusion Gene; FIG/ROS1 Fusion Gene; FIG1-ROS1 Fusion Gene; FIG-ROS1 Fusion Gene; GOPC-ROS1 Fusion Gene; ROS1/FIG Fusion Gene; GOPC::ROS1 Fusion Gene;

NCIt definition : A fusion gene ( 4.1 kb) that results from an interstitial deletion of 240 kb on 6q21 which fuses the first 7 exons of the GOPC gene to the last 9 exons of the ROS1 gene. This fusion is associated with glioblastoma multiforme.;

PubMed : 12661006;

Details

Origin ID

C99719;

UMLS CUI

C1847375;

Automatic exact mappings (from CISMeF team)
- Golgi-associated pdz and coiled-coil domains-containing protein [OMIM gene]
- Ros protooncogene 1, receptor tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GOPC/ROS1 Fusion Protein [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- GOPC Gene [NCIt concept]
- ROS1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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