SRGAP3/RAF1 Fusion Protein

Preferred Label : SRGAP3/RAF1 Fusion Protein;

NCIt synonyms : SLIT-ROBO Rho GTPase-Activating Protein 3/RAF Proto-Oncogene Serine/Threonine-Protein Kinase Fusion Protein; SRGAP3-RAF1 Fusion Protein; SRGAP3::RAF1 Fusion Protein;

NCIt definition : A fusion protein (931, 96 kDa) encoded by the SRGAP3/RAF1 fusion gene. This protein is comprised of the first 513 N-terminal amino acids of SLIT-ROBO Rho GTPase-activating protein 3, including the FCH domain, fused to 318 C-terminal amino acids of the RAF proto-oncogene serine/threonine-protein kinase protein, including the protein kinase domain.;

PubMed : 19363522;

Details

Origin ID

C99711;

UMLS CUI

C3274875;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- SRGAP3/RAF1 Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
related_to_genetic_biomarker
- RAF1 Gene [NCIt concept]
- SRGAP3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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