CNTRL/FGFR1 Fusion Protein

Preferred Label : CNTRL/FGFR1 Fusion Protein;

NCIt synonyms : CEP110-FGFR1 Fusion Protein; CEP1-FGFR1 Fusion Protein; CNTRL-FGFR1 Fusion Protein; Centriolin/Basic Fibroblast Growth Factor Receptor 1 Fusion Protein; CEP1/FGFR1 Fusion Protein; CEP110/FGFR1 Fusion Protein; CNTRL::FGFR1 Fusion Protein;

NCIt definition : A fusion protein encoded by the CNTRL/FGFR1 fusion gene. This protein is comprised of approximately 75% of the centriolin protein followed by the tyrosine kinase domains of the basic fibroblast growth factor receptor 1 protein.;

NCIt note : The CNTRL/FGFR1 fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Details

Origin ID

C99699;

UMLS CUI

C3274870;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CNTRL/FGFR1 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- CNTRL Gene [NCIt concept]
- FGFR1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients