FGFR1OP/FGFR1 Fusion Protein

Preferred Label : FGFR1OP/FGFR1 Fusion Protein;

NCIt synonyms : FGFR1 Oncogene Partner/Basic Fibroblast Growth Factor Receptor 1 Fusion Protein; FGFR1OP-FGFR1 Fusion Protein; FOP-FGFR1 Fusion Protein; FOP/FGFR1 Fusion Protein; CEP43::FGFR1 Fusion Protein; FGFR1OP::FGFR1 Fusion Protein;

NCIt definition : A fusion protein encoded by the FGFR1OP/FGFR1 fusion gene. This protein is comprised of the LIS1 homology domain of the FGFR1 oncogene partner protein followed by the tyrosine kinase domains of the basic fibroblast growth factor receptor 1.;

NCIt note : The FGFR1OP/FGFR1 fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Details

Origin ID

C99695;

UMLS CUI

C3274867;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FGFR1OP/FGFR1 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- CEP43 Gene [NCIt concept]
- FGFR1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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