TRIP11/PDGFRB Fusion Gene

Preferred Label : TRIP11/PDGFRB Fusion Gene;

NCIt synonyms : CEV14-PDGFRB Fusion Gene; CEV14/PDGFRB Fusion Gene; PDGFRB/TRIP11 Fusion Gene; TRIP11-PDGFRB Fusion Gene; TRIP11::PDGFRB Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(5;14)(q33;q32) which fuses the 5' part of the TRIP11 gene with the 3' part of the PDGFRB gene. This gene fusion is associated with chronic myelomonocytic leukemia.;

NCIt note : This fusion gene is found in conjunction with a chromosomal translocation t(7;11)(p15;p15) that results in the NUP98/HOXA9 fusion gene. (Atlas of Genetics and Cytogenetics in Oncology and Haematology);

Details

Origin ID

C99686;

UMLS CUI

C1858307;

Automatic exact mappings (from CISMeF team)
- Thyroid hormone receptor interactor 11 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- TRIP11/PDGFRB Fusion Protein [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- PDGFRB Gene [NCIt concept]
- TRIP11 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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