STAT5B/RARA Fusion Protein

Preferred Label : STAT5B/RARA Fusion Protein;

NCIt synonyms : Signal Transducer and Activator of Transcription 5B/Retinoic Acid Receptor Alpha Fusion Protein; STAT5B-RARA Fusion Protein; STAT5B::RARA Fusion Protein;

NCIt definition : A fusion protein encoded by the STAT5B/RARA fusion gene. This protein is comprised of the N-terminal coiled-coil, DNA binding, SH3 and SH2 domains of the signal transducer and activator of transcription 5B protein fused to the C-terminal transactivation, DNA binding, dimerization and ligand binding domains of the retinoic acid receptor alpha protein.;

PubMed : 18221386;

Details

Origin ID

C99667;

UMLS CUI

C3274858;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- STAT5B/RARA Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- RARA Gene [NCIt concept]
- STAT5B Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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