AKAP9/BRAF Fusion Protein

Preferred Label : AKAP9/BRAF Fusion Protein;

NCIt synonyms : AKAP9-BRAF Fusion Protein; A-Kinase Anchor Protein 9/Serine/Threonine-Protein Kinase B-Raf Fusion Protein; AKAP9::BRAF Fusion Protein; A-Kinase Anchor Protein 9::Serine/Threonine-Protein Kinase B-Raf Fusion Protein;

NCIt definition : A fusion protein (1492 aa, 172 kDa) encoded by the AKAP9/BRAF fusion gene. This protein is comprised of part of the A-kinase anchor protein 9 N-terminus fused to the C-terminal half of the serine/threonine-protein kinase B-raf protein.;

NCIt note : The AKAP9/BRAF fusion protein is a constitutively activated tyrosine kinase.;

Details

Origin ID

C99595;

UMLS CUI

C3467957;

Automatic exact mappings (from CISMeF team)
- A-kinase anchoring protein 9 [ORDO Gene]
- A-kinase anchoring protein 9 [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AKAP9/BRAF Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- AKAP9 Gene [NCIt concept]
- BRAF Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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