MLLT10/CLP1 Fusion Gene

Preferred Label : MLLT10/CLP1 Fusion Gene;

NCIt synonyms : AF10/HEAB Fusion Gene; HEAB/AF10 Fusion Gene; AF10-HEAB Fusion Gene; MLLT10-CLP1 Fusion Gene; MLLT10::CLP1 Fusion Gene;

NCIt definition : A fusion gene that results from a complex chromosomal rearrangement invins(10;11)(p12;q23q12) which fuses the 5' end of the MLLT10 gene with the 3' end of the CLP1 gene. This chromosomal aberration is associated with acute monoblastic leukemia.;

NCIt note : This fusion gene co-occurs with the MLL/MLLT10 fusion gene.;

Details

Origin ID

C99570;

UMLS CUI

C1865580;

Automatic exact mappings (from CISMeF team)
- Cleavage factor polynucleotide kinase subunit 1 [OMIM gene]
- Mllt10 histone lysine methyltransferase dot1l cofactor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Myeloid Leukemia with a Variant KMT2A Rearrangement [NCIt concept]
related_to_genetic_biomarker
- CLP1 Gene [NCIt concept]
- MLLT10 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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