" /> CCDC6/PDGFRB Fusion Protein - CISMeF





Preferred Label : CCDC6/PDGFRB Fusion Protein;

NCIt synonyms : H4/PDGFRB Fusion Protein; D10S170/PDGFRB Fusion Protein; Coiled-Coil Domain-Containing Protein 6/Beta-Type Platelet-Derived Growth Factor Receptor Fusion Protein; H4-PDGFRB Fusion Protein; CCDC6-PDGFRB Fusion Protein; Coiled-Coil Domain-Containing Protein 6::Beta-Type Platelet-Derived Growth Factor Receptor Fusion Protein; CCDC6::PDGFRB Fusion Protein;

NCIt definition : A fusion protein encoded by the CCDC6/PDGFRB fusion gene. This protein is comprised of the N-terminal leucine zipper of the coiled-coil domain-containing protein 6 fused to the C-terminal transmembrane and cytoplasmic domains of the beta-type platelet-derived growth factor receptor protein, including the protein kinase domain.;

NCIt note : The CCDC6/PDGFRB fusion protein is a constitutively dimerized and activated tyrosine kinase.;

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14/05/2024


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