" /> HIP1/PDGFRB Fusion Protein - CISMeF





Preferred Label : HIP1/PDGFRB Fusion Protein;

NCIt synonyms : Huntingtin-Interacting Protein 1/Beta-Type Platelet-Derived Growth Factor Receptor Fusion Protein; HIP1-PDGFRB Fusion Protein; HIP1::PDGFRB Fusion Protein;

NCIt definition : A fusion protein encoded by the HIP1/PDGFRB fusion gene. This protein is comprised of the first 950 amino acids of Huntingtin-interacting protein 1 fused to the C-terminal transmembrane and cytoplasmic domains of the beta-type platelet-derived growth factor receptor protein, including the protein kinase domain.;

NCIt note : The HIP1/PDGFRB fusion protein is a constitutively dimerized and activated tyrosine kinase.;

PubMed : 9616134;

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06/05/2025


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