NCIt definition : A fusion protein encoded by the HIP1/PDGFRB fusion gene. This protein is comprised
of the first 950 amino acids of Huntingtin-interacting protein 1 fused to the C-terminal
transmembrane and cytoplasmic domains of the beta-type platelet-derived growth factor
receptor protein, including the protein kinase domain.;
NCIt note : The HIP1/PDGFRB fusion protein is a constitutively dimerized and activated tyrosine
kinase.;