MLL/CBL Fusion Protein

Preferred Label : MLL/CBL Fusion Protein;

NCIt synonyms : MLL-CBL Fusion Protein; Histone-Lysine N-Methyltransferase MLL/E3 Ubiquitin-Protein Ligase CBL Fusion Protein; KMT2A::CBL Fusion Protein; MLL::CBL Fusion Protein;

NCIt definition : A fusion protein encoded by the MLL/CBL fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to the C-terminal proline-rich region and ubiquitin-binding leucine zipper domain of the E3 ubiquitin-protein ligase CBL protein.;

PubMed : 12696071;

Details

Origin ID

C99344;

UMLS CUI

C3274690;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- MLL/CBL Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- CBL Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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