MLL/GPHN Fusion Protein

Preferred Label : MLL/GPHN Fusion Protein;

NCIt synonyms : MLL-GPHN Fusion Protein; MLL/GPH Fusion Protein; MLL-GPH Fusion Protein; Histone-Lysine N-Methyltransferase MLL/Gephyrin Fusion Protein; MLL::GPHN Fusion Protein; KMT2A::GPHN Fusion Protein;

NCIt definition : A fusion protein encoded by the MLL/GPHN fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused with the C-terminus of the gephyrin protein including the presumed tubulin-binding site and a domain homologous to the E. coli molybdenum cofactor biosynthesis protein.;

Details

Origin ID

C99332;

UMLS CUI

C3274685;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- MLL/GPHN Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- GPHN Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients