BCR/FGFR1 Fusion Gene

Preferred Label : BCR/FGFR1 Fusion Gene;

NCIt synonyms : BCR/FGFR Gene; FGFR1/BCR Fusion Gene; BCR-FGFR1 Fusion Gene; BCR-FGFR Fusion Gene; BCR::FGFR1 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(8;22)(p11;q11) that fuses exon 4 of the BCR gene to exon 9 of the FGFR1 gene. This rearrangement is associated with 8p11 myeloproliferative disorder.;

Details

Origin ID

C99311;

UMLS CUI

C1851029;

Automatic exact mappings (from CISMeF team)
- Bcr activator of rhogef and gtpase [OMIM gene]
- Fibroblast growth factor receptor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BCR/FGFR1 Fusion Protein [NCIt concept]
gene_has_abnormality
- t(8;22)(p11;q11) [NCIt concept]
gene_involved_in_molecular_abnormality
- BCR-FGFR1 Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement [NCIt concept]
gene_mapped_to_disease
- Myeloid/Lymphoid Neoplasms with FGFR1 Rearrangement [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- BCR Gene [NCIt concept]
- FGFR1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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