EWSR1/ATF1 Fusion Protein

Preferred Label : EWSR1/ATF1 Fusion Protein;

NCIt synonyms : EWS-ATF1 Fusion Protein; RNA-Binding Protein EWS/Cyclic AMP-Dependent Transcription Factor ATF-1 Fusion Protein; EWSR1-ATF1 Fusion Protein; EWS/ATF1 Oncoprotein; EWSR1::ATF1 Fusion Protein;

NCIt definition : A fusion protein encoded by the EWSR1/ATF1 fusion gene. This protein is comprised of the transactivation domain of the RNA-binding protein EWS followed by the DNA-binding basic domain and leucine zipper dimerization domain of the cyclic AMP-dependent transcription factor ATF-1 protein.;

NCIt note : The EWSR1/ATF1 fusion protein is a constitutive activator of transcription.;

Details

Origin ID

C99218;

UMLS CUI

C3274614;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EWSR1/ATF1 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Transcriptional Activation [NCIt concept]
related_to_genetic_biomarker
- ATF1 Gene [NCIt concept]
- EWSR1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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