NUP214/ABL1 239 kDa Fusion Protein

Preferred Label : NUP214/ABL1 239 kDa Fusion Protein;

NCIt synonyms : Nuclear Pore Complex Protein Nup214/Tyrosine-Protein Kinase ABL1 239 kDa Fusion Protein; NUP214-ABL1 239 kDa Fusion Protein; NUP214::ABL1 239 kDa Fusion Protein;

NCIt definition : A fusion protein ( 239 kDa) encoded by the NUP214/ABL1 fusion gene variant 2. This protein is comprised of approximately half of the nuclear pore complex protein Nup214, which does not include the nucleoporin GLFG repeat domain, fused to the tyrosine-protein kinase ABL1 protein.;

NCIt note : The NUP214/ABL1 239 kDa fusion protein is a constitutively dimerized and activated tyrosine kinase.;

PubMed : 15361874;

Details

Origin ID

C99193;

UMLS CUI

C3274599;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- NUP214/ABL1 Fusion Gene Variant 2 [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ABL1 Gene [NCIt concept]
- NUP214 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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