Cefotiam Hexetil Hydrochloride

Preferred Label : Cefotiam Hexetil Hydrochloride;

NCIt synonyms : Cefotiam Hexetil HCl; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-,1-(((cyclohexyloxy)carbonyl)oxy)ethyl Ester, Dihydrochloride, (6R-(6-alpha,7-beta))-; CTM-HE Hydrochloride;

NCIt definition : The hydrochloride salt of the ester prodrug of cefotiam, a semi-synthetic, beta-lactam cephalosporin antibiotic, with antibacterial activity. After administration of cefotiam hexetil the ester bond is cleaved, releasing active cefotiam. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.;

UNII : 3N1X7E8CLE;

InChIKey : FFSANQNELHESQJ-LWBICVDYSA-N;

CAS number : 95789-30-3;

Drug name : Pansporin-T;

Chemical formula : C27H37N9O7S3.2ClH;

ChEBI ID : CHEBI:31373;

Détails

Origin ID

C98226;

UMLS CUI

C3273886;

CISMeF manual mappings
- cefotiam hexetil hydrochloride [International Nonproprietary Name]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cefotiam hexetil hydrochloride (substance) [SNOMED CT concept]
- cefotiam hexetil hydrochloride [International Nonproprietary Name]
Validated automatic mappings to NTBT
- cefotiam hexetil [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
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- Cefotiam Hexetil [NCIt concept]
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- Cefotiam Hexetil [NCIt concept]

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