Preferred Label : Cefotiam Hexetil;
NCIt synonyms : Cefotiam Hexetil Ester; CTM-HE; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-,1-(((cyclohexyloxy)carbonyl)oxy)ethyl
Ester, (6R,7R)-;
NCIt definition : The ester prodrug of cefotiam, a semi-synthetic, beta-lactam cephalosporin antibiotic,
with antibacterial activity. After administration of cefotiam hexetil the ester bond
is cleaved, releasing active cefotiam. Cefotiam binds to penicillin-binding proteins
(PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By
preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall
synthesis is halted.;
UNII : J92A81Y99T;
CAS number : 95761-91-4;
Origin ID : C217182;
concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
