TPM4 wt Allele

Preferred Label : TPM4 wt Allele;

NCIt synonyms : Tropomyosin 4 wt Allele; HEL-S-108;

NCIt definition : Human TPM4 wild-type allele is located in the vicinity of 19p13.1 and is approximately 35 kb in length. This allele, which encodes tropomyosin alpha-4 chain protein, plays a role in both cytoskeletal modeling and smooth muscle cell contraction. A chromosomal translocation t(2;19)(p23;p13.1) of this gene and the ALK gene is associated with inflammatory myofibroblastic tumors.;

GenBank Accession Number : NM_001145160;

Details

Origin ID

C97853;

UMLS CUI

C3273660;

OMIM relation
- Tropomyosin 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19p13.1 [NCIt concept]
gene_is_element_in_pathway
- Cardiac Muscle Contraction Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Muscle Contraction [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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