NCIt synonyms : TF6; SPG57; TRKT3; FLJ36137; TRKT3 Oncogene; Trafficking from ER to Golgi Regulator wt Allele; HMSNP; TRK-Fused Gene;
NCIt definition : Human TFG wild-type allele is located in the vicinity of 3q12.2 and is approximately
40 kb in length. This allele, which encodes protein TFG, plays a role in the modulation
of signaling. A chromosomal translocation t(2;3)(p23;q21) of this gene and the ALK
gene is associated with anaplastic large cell lymphoma. A second translocation t(1;3)(q21;q11)
of this gene and the NTRK1 gene is associated with thyroid papillary carcinoma. A
third translocation of this gene and the NR4A3 gene is associated with extraskeletal
myxoid chondrosarcoma.;