FOXP1 wt Allele

Preferred Label : FOXP1 wt Allele;

NCIt synonyms : Fork Head-Related Protein Like B Gene; MGC12942; FLJ23741; Glutamine-Rich Factor 1 Gene; 12CC4; HSPC215; hFKH1B; Forkhead Box P1 wt Allele; MGC88572; QRF1; MGC99551;

NCIt definition : Human FOXP1 wild-type allele is located in the vicinity of 3p14.1 and is approximately 629 kb in length. This allele, which encodes forkhead box protein P1, plays a role in the negative regulation of transcription. Mutation of the gene is associated with mental retardation with language impairment and autistic features. A translocation t(9;3)(p13;p14.1) of this gene with the PAX5 gene is associated with acute lymphoblastic leukemia.;

GenBank Accession Number : AF146696;

Details

Origin ID

C97550;

UMLS CUI

C3273484;

Automatic exact mappings (from CISMeF team)
- Forkhead box p1 [OMIM gene]
- forkhead box P1 [ORDO Gene]
OMIM relation
- Forkhead box p1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p14.1 [NCIt concept]
gene_plays_role_in_process
- B-Cell Differentiation [NCIt concept]
- DNA Binding [NCIt concept]
- Epithelial Cell Proliferation [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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