CD74 wt Allele

Preferred Label : CD74 wt Allele;

NCIt synonyms : Ii; Ia-GAMMA; MHC HLA-DR Gamma Chain Gene; HLA-DR-Gamma Gene; Gamma Chain of Class II Antigens Gene; HLADG; Ia-Associated Invariant Chain Gene; DHLAG; CD74 Molecule wt Allele; CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain Gene;

NCIt definition : Human CD74 wild-type allele is located in the vicinity of 5q32 and is approximately 11 kb in length. This allele, which encodes HLA class II histocompatibility antigen gamma chain protein, is involved in MHC class II antigen processing and presentation. A translocation of this gene and the ROS1 gene may be associated with non-small cell lung cancer.;

GenBank Accession Number : NM_001025158;

Details

Origin ID

C97419;

UMLS CUI

C3273406;

OMIM relation
- Cd74 antigen [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q32 [NCIt concept]
gene_is_element_in_pathway
- Antigen Presentation Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
gene_plays_role_in_process
- Antigen Presentation [NCIt concept]
- Humoral Immunity [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction Induction [NCIt concept]

Keyword's position in hierarchy(ies) :

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