Preferred Label : Clonidine-containing Mucoadhesive Buccal Tablet;
NCIt synonyms : Clonidine Lauriad;
NCIt definition : An extended release, proprietary mucoadhesive buccal tablet formulation containing
the hydrochloride salt form of clonidine, the imidazoline derivative and adrenergic
alpha 2 receptor agonist, with anti-inflammatory activity. Upon contact of the tablet
with the buccal mucosa, clonidine binds to the adrenergic receptors on macrophages
and lymphocytes and may reduce the release of pro-inflammatory mediators such as tumor
necrosis factor alpha (TNFalpha). As a result, this agent may prevent chemoradiation
therapy-induced mucositis.;
NCI Metathesaurus CUI : CL429823;
Origin ID : C97329;
UMLS CUI : C3273363;
Semantic type(s)
- concept_is_in_subset
- has_target
