Epithelial-to-Mesenchymal Transition

Preferred Label : Epithelial-to-Mesenchymal Transition;

NCIt synonyms : EMT; Epithelial-Mesenchymal Transition; Epithelial to Mesenchymal Transition; Epithelial Mesenchymal Transition;

NCIt definition : A cellular process where an epithelial cell loses polarity, disassembles adhesive junctions, degrades its basement membrane and transforms into a migratory mesenchymal cell.;

NCIt note : This process occurs during embryo developmental processes such as cardiac development and has been hypothesized to be an important step in oncogenic transformation.;

Details

Origin ID

C97304;

UMLS CUI

C1523298;

Automatic exact mappings (from CISMeF team)
- Epithelial-Mesenchymal transition [MeSH Descriptor]
- Epithelial-Mesenchymal transition [MeSH concept]
- Epithelial-to-mesenchymal transformation [FMA entity]
- IL2 inducible T cell kinase [ORDO Gene]
- Il2-inducible t-cell kinase [OMIM gene]
- Paramedic (occupation) [SNOMED CT concept]
- Solute carrier family 22 (extraneuronal monoamine transporter), member 3 [OMIM gene]
- epithelial to mesenchymal transition [GO term]
- mesenchymal to epithelial transition [GO term]
- thalamic eminence [UBERON concept]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- Epithelial-Mesenchymal transition [MeSH concept]
- Epithelial-Mesenchymal transition [MeSH Descriptor]
- Epithelial-to-mesenchymal transformation [FMA entity]
- epithelial to mesenchymal transition [GO term]
- mesenchymal to epithelial transition [GO term]
biological_process_has_associated_location
- Cell [NCIt concept]
biological_process_has_initiator_process
- Intercellular Communication Process [NCIt concept]
biological_process_involves_gene_product
- B-Cell CLL/Lymphoma 9-Like Protein [NCIt concept]
- Brain Acid Soluble Protein 1 [NCIt concept]
- Endotrophin [NCIt concept]
- Heterogeneous Nuclear Ribonucleoprotein A/B [NCIt concept]
- Protein Crumbs Homolog 2 [NCIt concept]
- Protein FAM3C [NCIt concept]
- Protein S100-A4 [NCIt concept]
- Transforming Growth Factor Beta-1-Induced Transcript 1 Protein [NCIt concept]
biological_process_is_part_of_process
- Histogenic Process [NCIt concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
process_involves_gene
- BASP1 Gene [NCIt concept]
- BASP1 wt Allele [NCIt concept]
- BCL9L Gene [NCIt concept]
- BCL9L wt Allele [NCIt concept]
- CRB2 Gene [NCIt concept]
- CRB2 wt Allele [NCIt concept]
- FAM3C Gene [NCIt concept]
- FAM3C wt Allele [NCIt concept]
- HNRNPAB Gene [NCIt concept]
- HNRNPAB wt Allele [NCIt concept]
- S100A4 Gene [NCIt concept]
- S100A4 wt Allele [NCIt concept]
- TGFB1I1 Gene [NCIt concept]
- TGFB1I1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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