NCIt definition : A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin
with potential antineoplastic activity. Esorubicin intercalates into DNA and inhibits
topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with
RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent
antibiotic doxorubicin, but may cause more severe myelosupression compared to other
compounds within the anthracycline class.;