Esorubicin - CISMeF

Preferred Label : Esorubicin;

NCIt synonyms : Deoxyadriamycin; 4'-Deoxydoxorubicin; 4'-Deoxyadriamycin;

NCIt related terms : Deoxydoxorubicin;

NCIt definition : A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause more severe myelosupression compared to other compounds within the anthracycline class.;

UNII : RMC41L2WQ3;

InChIKey : ITSGNOIFAJAQHJ-BMFNZSJVSA-N;

CAS number : 63521-85-7;

Molecule name : IMI-58;

Chemical formula : C27H29NO10;

NSC code : 267469;

Codes from synonyms : NSC0267469;

Détails

Origin ID

C972;

UMLS CUI

C0047760;

Currated CISMeF NLP mapping
- esorubicin [MeSH concept]
- esorubicin [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- esorubicin [MeSH concept]
- esorubicin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Esorubicin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Esorubicin Hydrochloride [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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