" /> Esorubicin Hydrochloride - CISMeF





Preferred Label : Esorubicin Hydrochloride;

NCIt synonyms : 4'-Deoxyadriamycin HCl; 4'-Deoxydoxorubicin HCl; (2S-(2alpha(8R*,10R*),4beta,6beta))-10-((4-Aminotetrahydro-6-methyl-2H-pyran-2-yl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione Hydrochloride; Deoxydoxorubicin HCI;

NCIt definition : A hydrochloride salt of esorubicin, a derivative of the anthracycline antineoplastic antibiotic doxorubicin, with potential antineoplastic activity. Esorubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause more severe myelosupression compared to other compounds within the anthracycline class.;

UNII : 2UB1JJT82D;

InChIKey : RCFNNLSZHVHCEK-YGCMNLPTSA-N;

CAS number : 63950-06-1;

Chemical formula : C27H29NO10.HCl;

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28/07/2025


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