Preferred Label : Esorubicin Hydrochloride;
NCIt synonyms : 4'-Deoxyadriamycin HCl; 4'-Deoxydoxorubicin HCl; (2S-(2alpha(8R*,10R*),4beta,6beta))-10-((4-Aminotetrahydro-6-methyl-2H-pyran-2-yl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione
Hydrochloride; Deoxydoxorubicin HCI;
NCIt definition : A hydrochloride salt of esorubicin, a derivative of the anthracycline antineoplastic
antibiotic doxorubicin, with potential antineoplastic activity. Esorubicin intercalates
into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately,
interfering with RNA and protein synthesis. This agent exhibits less cardiotoxicity
than the parent antibiotic doxorubicin, but may cause more severe myelosupression
compared to other compounds within the anthracycline class.;
UNII : 2UB1JJT82D;
InChIKey : RCFNNLSZHVHCEK-YGCMNLPTSA-N;
CAS number : 63950-06-1;
Chemical formula : C27H29NO10.HCl;
Origin ID : C74943;
UMLS CUI : C0955070;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
