Preferred Label : TPO Receptor Agonist ONO-7746;
NCIt definition : An orally available small molecule and platelet thrombopoietin (TPO) receptor (TPOR;
MPL) agonist with potential megakaryopoiesis stimulating activity. Upon administration,
TPOR agonist ONO-7746 binds to and stimulates TPOR, which may lead to the proliferation
and differentiation of megakaryocytes. In turn, this may increase the production of
blood platelets and may prevent chemotherapy induced thrombocytopenia (CIT). TPOR
is a cytokine receptor and member of the hematopoietin receptor superfamily.;
Molecule name : ONO-7746;
NCI Metathesaurus CUI : CL429407;
Origin ID : C96800;
UMLS CUI : C3273042;
Semantic type(s)
- concept_is_in_subset
- has_target
