" /> Cevipabulin Succinate - CISMeF





Preferred Label : Cevipabulin Succinate;

NCIt synonyms : 5-chloro-6-(2,6-difluoro-4-(3-(methylamino)propoxy)phenyl)-N-((1S)-2,2,2-trifluoro-1-methylethyl)(1,2,4)triazolo(1,5-a)pyrimidin-7-amine succinate dihydrate;

NCIt definition : The succinate salt form of cevipabulin, a synthetic, water soluble tubulin-binding agent with potential antineoplastic activity. Cevipabulin binds at the vinca-binding site on tubulin, but seems to act more similar to taxane-site binding agents in that it enhances tubulin polymerization and does not induce tubulin depolymerization. This stabilizes tubulin and prevents microtubule disassembly. The disruption in microtubule dynamics may eventually inhibit cell division and reduce cellular growth.;

UNII : 8XI0CX98LY;

InChIKey : FWNIBMRSBSSPNP-DXYFNVQQSA-N;

CAS number : 852954-81-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 852954-81-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : TTI-237 Succinate Dihydrate;

Chemical formula : C18H18ClF5N6O.C4H6O4.2H2O;

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12/05/2024


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