NCIt definition : The triphosphate salt of cordycepin, a purine nucleoside antimetabolite and antibiotic
isolated from the fungus Cordyceps militaris with potential antineoplastic, antioxidant,
and anti-inflammatory activities. Cordycepin is an inhibitor of polyadenylation, activates
AMP-activated protein kinase (AMPK), and reduces mammalian target of rapamycin (mTOR)
signaling, which may result in both the induction of tumor cell apoptosis and a decrease
in tumor cell proliferation. mTOR, a serine/threonine kinase belonging to the phosphatidylinositol
3-kinase (PI3K)-related kinase (PIKK) family, plays an important role in the PI3K/AKT/mTOR
signaling pathway that regulates cell growth and proliferation, and its expression
or activity is frequently dysregulated in human cancers.;
UNII : 59P84ZU54H;
InChIKey : NLIHPCYXRYQPSD-BAJZRUMYSA-N;
CAS number : 73-04-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 73-04-1
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