Calponin - CISMeF

Preferred Label : Calponin;

NCIt definition : A family of actin and calcium binding proteins found mostly in smooth muscle-containing tissues. These proteins play a role in the regulation of actin/myosin interactions and the subsequent mediation of smooth muscle contraction.;

NCIt note : There are three calponin proteins encoded by distinct genes. Calponin-1 and calponin-2 are expressed in smooth muscle. Calponin-3 is expressed at low levels in smooth muscle and is also expressed by some non-muscle tissues.;

Details

Origin ID

C96483;

UMLS CUI

C0054541;

Currated CISMeF NLP mapping
- Calponin [LOINC component]
- Calponins [MeSH Descriptor]
- calponin [MeSH Supplementary Concept]
- calponin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Calponin [LOINC component]
- Calponins [MeSH Descriptor]
- calponin [MeSH Supplementary Concept]
- calponin [MeSH concept]
gene_product_expressed_in_tissue
- Smooth Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
- Calcium Binding Protein [NCIt concept]
- Cytoskeletal Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Muscle Contraction [NCIt concept]

Keyword's position in hierarchy(ies) :

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