CD274 wt Allele

Preferred Label : CD274 wt Allele;

NCIt synonyms : PDCD1L1; CD274 Molecule wt Allele; PDCD1LG1; PD-L1; PDL1; MGC142294; Programmed Cell Death 1 Ligand 1 Gene; B7-H; MGC142296; B7H1; CD274 Antigen Gene;

NCIt definition : Human CD274 wild-type allele is located in the vicinity of 9p24 and is approximately 20 kb in length. This allele, which encodes programmed cell death 1 ligand 1 protein, plays a role in the regulation of T cell stimulation and proliferation.;

NCIt note : Fusion of the CD274 gene and the CITTA gene may be associated with lymphoid cancers. (Nature 2011; doi:10.1038/nature09754.);

GenBank Accession Number : AF177937;

Details

Origin ID

C96023;

UMLS CUI

C3272500;

OMIM relation
- Cd274 molecule [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 9p24 [NCIt concept]
gene_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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